主题:Quantile Cure Models
主讲人:彭英伟 加拿大女王大学
主持人:刘晓玉 暨南大学
时间:2026年7月10日(周五)上午10:30-11:30
地点:暨南大学石牌校区经济学院(中惠楼)102室
摘要
The quantile regression offers several attractive features, including the ability to allow covariate effects to vary at different quantile levels and to effectively handle heteroscedasticity in data, which makes it a viable alternative for analyzing data with continuous outcomes in recent years. It has been used in modeling survival data with and without a cured fraction. In this talk, I will review some existing quantile cure models and introduce novel estimating equation approaches we proposed recently to estimate a mixture cure model where the latency survival time is modeled using a quantile regression. Our proposed estimation methods provide double robustness, relax the restrictive global log-linear assumption, and allow for both quantile-varying and quantile-invariant effects in the regression. We established the asymptotic properties of the proposed estimators, and our simulation studies demonstrated their double robustness and efficiency gains. An application of the proposed model and methods to data from a lung cancer study revealed that uncured patients with adenocarcinoma have significantly longer quantiles in the survival time than uncured patients with squamous cell carcinoma, which had not been reported in previous analyses of the data due to the limitations of the existing methods.
主讲人简介

彭英伟教授,现为加拿大女皇大学数学与统计系和公共健康科学系教授,同时也是Cancer Care and Epidemiology Division of Cancer Research Institute的资深生物统计分析师,曾受聘为密歇根大学和大连理工大学的客座教授。其在Biometrics、Statistics in Medicine、Computational Statistics & Data Analysis、Canadian Journal of Statistics等国际主流统计期刊发表论文80余篇,单篇文章最高被引用280余次。主持或参与美国国立卫生研究院(NIH)、加拿大自然科学与工程研究理事会(NSERC)等科研基金项目共20余项。目前担任加拿大卫生研究院(CIHR)、加拿大自然科学与工程研究理事会(NSERC)、加拿大国立癌症研究所(NCIC)、瑞士自然科学等基金评审委员会成员。曾任国际著名统计期刊Canadian Journal of Statistics和Statistics in Biosciences的副主编、Journal of Urology统计学家委员会成员,以及Mathematical Review的审稿人。此外,他还担任过泛华统计协会(ICSA)加拿大分会主席、多次担任ICSA会议的组织者或组委会成员,并曾任加拿大统计学会(SSC)Pierre Robillard奖委员会主席。
校对 |刘晓玉
责编 | 彭毅
初审 | 姜云卢
终审发布 | 何凌云
(来源:暨南大学经济学院微信公众号)

